Aggressive breast cancer cells are dependent on activated Abl kinases for proliferation, anchorage-independent growth and survival.

SHP-2 is a novel target of Abl kinases during cell proliferation.

Reciprocal regulation of Abl and receptor tyrosine kinases.

MTT assays cannot be utilized to study the effects of STI571/Gleevec on the viability of solid tumor cell lines.

STI571 sensitizes breast cancer cells to 5-fluorouracil, cisplatin and camptothecin in a cell type-specific manner.

Enhanced resistance to tamoxifen by the c-ABL proto-oncogene in breast cancer.

c-Abl and Arg are activated in human primary melanomas, promote melanoma cell invasion via distinct pathways, and drive metastatic progression.

c-Abl and Arg are activated in human primary melanomas, promote melanoma cell invasion via distinct pathways, and drive metastatic progression.

[Anonymous].  2012.  c-Abl and Arg are activated in human primary melanomas, promote melanoma cell invasion via distinct pathways, and drive metastatic progression.. Oncogene. 31(14):1804-16.

Activation of abl family kinases in solid tumors.

Imatinib reverses doxorubicin resistance by affecting activation of STAT3-dependent NF-κB and HSP27/p38/AKT pathways and by inhibiting ABCB1.

Imatinib reverses doxorubicin resistance by affecting activation of STAT3-dependent NF-κB and HSP27/p38/AKT pathways and by inhibiting ABCB1.

[Anonymous].  2013.  Imatinib reverses doxorubicin resistance by affecting activation of STAT3-dependent NF-κB and HSP27/p38/AKT pathways and by inhibiting ABCB1.. PloS one. 8(1):e55509.

Search for High-Mass Resonances Decaying to τν in pp Collisions at sqrt s =13  TeV with the ATLAS Detector.